Working on the Feeding Grounds, my upcoming Darwin's World adventure for my upcoming Darwin's World setting (coming to a GenCon near you I think) and I'm trying to wrap my mind around the city the adventure is set in.
It's sort of Dawn of the Dead. It's definitely a horror setting. I'm also trying to decide how to handle the issue of people who went to sleep (cryo sleep centuries ago) in paradise and woke up in hell.
Probably not realistically. Save vs. straightjacket doesn't make for good adventuring most of the time.